Both Tadalafil and Sildenafil are PDE5 inhibitors used for erectile dysfunction, but they differ in duration, onset, and lifestyle use. Tadalafil (Cialis) Onset: ~30β60 minutes Half-life: ~17.5 hours Duration: Up to 36 hours (βthe weekend pillβ) Use case: Flexible timing β can be taken daily (low dose) or as needed Better for long-term spontaneity Also
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