Description
Dapoxetine HCL (Dapoxetine Hydrochloride) is a short-acting selective serotonin reuptake inhibitor (SSRI) developed specifically for the treatment of premature ejaculation (PE) in men.
Key Facts
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Drug class: Short-acting SSRI
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Purpose: Delays ejaculation by increasing serotonin activity in the nervous system, which helps improve control over ejaculation timing.
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Onset & Duration:
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Rapid absorption — works within 1–3 hours after oral intake
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Short half-life (~1.5 hours), so it’s taken on-demand, not daily
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Medical Uses
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Primary indication: Premature ejaculation in adult men
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Not intended for depression or anxiety treatment due to its very short duration of action
Dosage
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Starting dose: 30 mg, taken 1–3 hours before sexual activity
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If tolerated but insufficient: May increase to 60 mg (max dose)
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Not for daily continuous use — should only be taken when needed
Side Effects
Common:
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Nausea
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Dizziness
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Headache
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Diarrhea
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Insomnia
Less common / rare:
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Fainting (especially if combined with alcohol or certain drugs)
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Mood changes
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Vision disturbances
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