Description
Sildenafil is the active ingredient in the original Viagra — but it’s also sold under other names and brands. While many ED (erectile dysfunction) medications seem similar, there are key differences in active ingredient, onset, duration, and effect on the body.
1. What is Sildenafil?
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Chemical Name: Sildenafil Citrate
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Brand Name: Viagra (by Pfizer)
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Use: Treats erectile dysfunction and sometimes pulmonary hypertension
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How it works: Inhibits PDE5 enzyme, increasing blood flow to the penis during sexual stimulation
Sildenafil vs. Other ED Drugs
| Drug | Brand Example | Onset Time | Duration | Notes |
|---|---|---|---|---|
| Sildenafil | Viagra | 30–60 mins | 4–6 hours | Best on empty stomach |
| Tadalafil | Cialis | 30–60 mins | Up to 36 hours | Known as the “weekend pill” |
| Vardenafil | Levitra, Staxyn | 30–60 mins | 4–6 hours | Similar to Viagra, often gentler on digestion |
| Avanafil | Stendra | 15–30 mins | 6 hours | Fastest-acting ED drug |
What Makes Sildenafil (Viagra) Unique?
Fast & Reliable
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Works in 30–60 minutes, with a long track record of effectiveness.
Highly Studied & Widely Used
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One of the first and most researched ED treatments available.
Affordable Generics Available
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After Viagra’s patent expired, many generic versions of sildenafil became available — same effect at a lower price.
Food Sensitivity
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Works best on an empty stomach; fatty meals may delay or reduce effectiveness.
Limitations Compared to Other ED Meds
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Shorter duration than Tadalafil (Cialis)
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Less fast-acting than Avanafil (Stendra)
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Can cause more flushing, headaches, or nasal congestion in some users
When to Choose Sildenafil:
You want a reliable, proven ED treatment You don’t need it to last all day (just 4–6 hours) You’re okay with timing your dose before activity You want a lower-cost generic option
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