GW501516 10

Description

GW501516 (also called Cardarine or Endurobol) is a synthetic compound developed in the 1990s by GlaxoSmithKline and Ligand Pharmaceuticals.

It is not a SARM (selective androgen receptor modulator), though people often group it together with SARMs in bodybuilding circles. Instead, it is a PPARδ (peroxisome proliferator-activated receptor delta) agonist.

🔬 How it works
Activates PPARδ, a receptor that regulates fat metabolism, glucose uptake, and endurance-related genes.

Increases the body’s ability to use fatty acids as energy, sparing glycogen.

Enhances endurance and stamina (athletes sometimes call it “exercise in a pill”).

⚡ Effects (as reported in studies and bodybuilding use)
Significant increase in endurance and stamina.

Promotes fat burning (shifts metabolism toward lipid oxidation).

May improve cholesterol profile (↑ HDL, ↓ LDL).

No androgenic or anabolic activity (doesn’t affect testosterone directly).

💊 Use in sports / bodybuilding
Often used in cutting phases to burn fat while preserving muscle.

Popular with endurance athletes (cycling, running) due to stamina increase.

Typical informal usage reported: 10–20 mg/day for 6–8 weeks (oral).

Frequently combined with SARMs (e.g., Ostarine, Ligandrol) in “stacks.”

⚠️ Risks and controversies
In animal studies, long-term use caused cancer in mice at high doses.

Because of this, all human trials were stopped around 2007.

WADA banned it in 2009; it is on the prohibited list for athletes.

Unknown long-term safety in humans (no approved medical use).

✅ In short:
GW501516 (Cardarine) is a PPARδ agonist that boosts endurance and fat metabolism, widely used in bodybuilding despite health risks and its ban in professional sports.

Do you want me to break down the difference between GW501516 and SARMs (since they’re often confused), or would you rather see a practical comparison to something like Clenbuterol?