SEMAX

Description

What is Semax?

• Category: Synthetic nootropic & neuroprotective peptide.

• Structure: An analog of adrenocorticotropic hormone (ACTH 4-10 fragment), but modified to enhance stability and effectiveness.

• Origin: Developed in Russia in the 1980s–90s for medical use.

How it Works

Semax primarily acts on the central nervous system, where it:

• Increases levels of BDNF (Brain-Derived Neurotrophic Factor) → supports neuron growth, plasticity, and survival.

• Modulates neurotransmitters like dopamine and serotonin, improving cognitive balance.

• Provides neuroprotection against stress, hypoxia (low oxygen), and toxins.

Applications

• Medical use (Russia): Treatment of stroke recovery, cognitive impairment, and memory loss.

• Nootropic use: Enhances focus, learning, memory, and mental clarity.

• Neuroprotection: Helps protect the brain during stress or oxygen deprivation.

• Mood regulation: Mild anxiolytic effects without sedation.

Administration

• Usually applied as a nasal spray for fast delivery to the brain.

• Sometimes used in injections in clinical settings.

Side Effects

• Generally well tolerated.

• Possible mild irritation in nasal passages, headaches, or restlessness.

• No major reports of dependency or withdrawal.

✅ Summary:
Semax is a neuroprotective nootropic peptide that boosts brain function, protects neurons, and supports recovery from stress or injury. Unlike stimulants, it enhances focus and cognition naturally, making it popular both in clinical neurology and the nootropic community.